Application

Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected NEGR1 in human cerebellum and rat cerebral cortex tissue.

Research CategoryNeuroscience

Research Sub CategoryDevelopmental Signaling

This Anti-NEGR1, clone 4H2.1 Antibody is validated for use in Western Blotting and Immunohistochemistry (Paraffin) for the detection of NEGR1.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Neuronal growth regulator 1 (NEGR1) is also called IgLON family member 4. NEGR1 belongs to the immunoglobulin superfamily and is thought to be involved in cell-adhesion. NEGR1 possibly functions as a trans-neural growth-promoting factor in regenerative axon sprouting in the mammalian brain.

Immunogen

GST-tagged recombinant protein corresponding to human NEGR1.

Linkage

Replaces: MABN1072

Other Notes

Concentration: Please refer to lot specific datasheet.

Physical form

Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Protein G Purified

Format: Purified

Quality

Evaluated by Western Blotting in human hippocampus tissue lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected NEGR1 in 10 µg of human hippocampus tissue lysate.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Target description

~50 kDa observed